Lentivirus Transduction Enhancer I

Lentivirus Transduction Enhancer I (1 ml )

Lentivirus Transduction Enhancer I is a novel chemical reagent that increases lentiviral transduction efficiency into in vitro systems. Normally, incubation of lentivirus particles in cells in the presence of polybrene is generally efficient in transducing many cell types. However, lentiviruses are typically attenuated by cellular antiviral defense mechanism, which limits their transducing efficiency. Lentivirus Transduction Enhancer I suppresses the cellular anti-viral state by mimicking the activity of viral virulence gene products, and thus significantly increases lentivirus transducing efficiency by as high as 10-fold.