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Donor plasmid design and synthesis for Knock-In (KI) and Gene Correction through Homologous Recombination (HR). To be used with engineered nucleases (ZFNs, TALENs and RGENs/CRISPRs) Learn More

Genome-TALER™ human AAVS1 safe harbor gene targeting kit is designed to specifically transfer your gene of interest, selection marker or other genetic element from a donor plasmid into the AAVS1 safe harbor site in human chromosome 19 via TALEN-mediated homologous recombination Learn More

Human cell line CAMA-1 stably expressing CRISPR Cas9 (indicated price is for Academic; Industrial customers please inquire) Learn More

Human cell line SNU-1 stably expressing Cas9, randomly inserted, single clone (indicated price is for Academic; Industrial customers please inquire)

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Human cell line CFPAC-1 stably expressing Cas9, randomly inserted, single clone (indicated price is for Academic; Industrial customers please inquire)

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Human cell line SK-HEP-1 stably expressing CRISPR Cas9, randomly inserted, single clone (indicated price is for Academic; Industrial customers please inquire)

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Cloning vector for donor DNA construction Includes MCS, eGFP reporter, and Puromycin marker Learn More

A key application for TALEs is the targeted activation and repression of target genes in cells by fusing transactivation domains to TALE DNA binding domains . The TALE-TF construct is a powerful tool to selectively modulate gene expression in eukaryotic c Learn More

RNA-Guided ENdonucleases (RGENs) are novel, programmable genome engineering tools that were developed from bacterial adaptive immune machinery. In this system—the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) i Learn More

The surrogate reporter system allows for quick and efficient enrichment of cells effectively modified by ZFNs, TALENs or CRISPRs (RGENs) Learn More