Donor plasmid design and synthesis for Knock-In (KI) and Gene Correction through Homologous Recombination (HR). To be used with engineered nucleases (ZFNs, TALENs and RGENs/CRISPRs) Learn More
A key application for TALEs is the targeted activation and repression of target genes in cells by fusing transactivation domains to TALE DNA binding domains . The TALE-TF construct is a powerful tool to selectively modulate gene expression in eukaryotic c Learn More
TAL Effector nucleases (TALENs) are artificial restriction enzymes, created by fusing an engineered TAL DNA binding domain
(which targets a desired sequences) with the DNA cleavage domain of FokI, a type II restriction enzyme. Learn More
Zinc finger nucleases (ZFNs) are artificial restriction enzymes, created by fusing an engineered zinc finger DNA binding domain
(which targets a desired sequences) with the DNA cleavage domain of FokI, a type II restriction enzyme. Learn More
RNA-Guided ENdonucleases (RGENs) are novel, programmable genome engineering tools that were developed from bacterial adaptive immune machinery. In this system—the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) i Learn More
AAVS1 CRISPR system designed to integrate a gene of interest or any other genetic element into the AAVS1 safe harbor site in human chromosome 19 via homologous recombination. Learn More
AAVS1 CRISPR system designed to integrate a gene of interest or any other genetic element into the AAVS1 safe harbor site in human chromosome 19 via homologous recombination. Learn More
Genome-TALER™ human AAVS1 safe harbor gene targeting kit is designed to specifically transfer your gene of interest, selection marker or other genetic element from a donor plasmid into the AAVS1 safe harbor site in human chromosome 19 via TALEN-mediated homologous recombination Learn More
TAL Effector nucleases (TALENs) are artificial restriction enzymes, created by fusing an engineered TAL DNA binding domain
(which targets a desired sequences) with the DNA cleavage domain of FokI, a type II restriction enzyme. Learn More
TAL Effector nucleases (TALENs) are artificial restriction enzymes, created by fusing an engineered TAL DNA binding domain
(which targets a desired sequences) with the DNA cleavage domain of FokI, a type II restriction enzyme. Learn More
Donor plasmid design & synthesis0,00 €Donor plasmid design and synthesis for Knock-In (KI) and Gene Correction through Homologous Recombination (HR). To be used with engineered nucleases (ZFNs, TALENs and RGENs/CRISPRs) Learn More
TAL Effector Nucleases0,00 €TAL Effector nucleases (TALENs) are artificial restriction enzymes, created by fusing an engineered TAL DNA binding domain (which targets a desired sequences) with the DNA cleavage domain of FokI, a type II restriction enzyme. Learn More
AAVS1 Safe Harbour Integration-TALEN tools and services0,00 €Genome-TALER™ human AAVS1 safe harbor gene targeting kit is designed to specifically transfer your gene of interest, selection marker or other genetic element from a donor plasmid into the AAVS1 safe harbor site in human chromosome 19 via TALEN-mediated homologous recombination Learn More