TFF-EVs-MV- tangential flow filtration-based device
TFF-EVs-MV- tangential flow filtration-based device
TFF-EVs-MV- tangential flow filtration-based device
Tangential flow filtration (TFF) is emerging as one of the most efficient methods for the purification of extracellular vesicles. The TFF-EVs filter allows a rapid, reproducible and scalable purification of EVs. It can be used on the lab bench for purifying small volume of samples or connected with a mechanical system for purifying larger volumes. During the purification, the sample is simultaneously concentrated.
TFF-EVs-MV- tangential flow filtration-based device can be easily washed and it is reusable multiple times.
Applications: Separation of EVs by size ; Recovering of big microvesicles in one step, without additional purification
Advantages: Washable, reusable multiple times, easy to use, fast concentration of EV containing matrices. EV dialysis.
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Sample type |
Diluted EV containing matrices (i.e. urine, conditioned cell media) |
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Quantity |
1 concentrator. |
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Product overview |
TFF-MV is a filter cartridge in hollow fibers made of polysulfone. The filter is very useful for separating different EVs by size. Indeed, microvesicles bigger than 150 nm are retained inside the hollow fibers, while small EVs and molecules easily permeate the filter. Microvesicles can be recovered with a syringe in PBS buffer without additional purification steps.EV recovery: 83 % Reusable multiple times (20 X max) |
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Volume of sample |
10 ml up to several liters if connected to mechanical pump. |
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Shipment and storage |
Room temperature. |
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Expiration date |
24 months. |
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Applications |
Fast and scalable EV purification and concentration
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Sterility |
Sterile. (e-beams sterilization) |