TFF-EVs-Large- tangential flow filtration-based device
TFF-EVs-Large- tangential flow filtration-based device
TFF-EVs-Large- tangential flow filtration-based device
Tangential flow filtration (TFF) is emerging as one of the most efficient methods for the purification of extracellular vesicles. The TFF-EVs filter allows a rapid, reproducible and scalable purification of EVs. It can be used on the lab bench for purifying small volume of samples or connected with a mechanical system for purifying larger volumes. During the purification, the sample is simultaneously concentrated.
TFF-EVs-Large- tangential flow filtration-based device can be easily washed and it is reusable multiple times.
Applications: Fast and scalable EV purification and concentration, for example for depletion of FBS from bovine EVs or Particle buffer exchange and removal of unbound dye
Advantages: Washable, reusable multiple times, easy to use, fast concentration of EV containing matrices. EV dialysis.
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Sample type |
EVs containing matrices (i.e. urine, conditioned cell media, plasma, serum, plant extracts) |
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Quantity |
1 concentrator. |
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Product overview |
Filter cartridge made of polyethersulfone hollow fibers (50 nm pores). Filtering surface: 1 m2 Cut-off: 800 KDa EV recovery: 81 % Internal fiber diameter (μm): 210 Maximum flow rate (ml/min): -Conditioned media: 115 ml/min -Urine: 100 ml/min -viscous fluids (plasma, serum): 78 ml/min Reusable multiple times |
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Volume of sample |
500 ml to 10 000 ml |
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Shipment and storage |
Room temperature. |
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Expiration date |
24 months. |
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Applications |
Fast and scalable EV purification and concentration • Depletion of FBS from bovine EVs • Particle buffer exchange and removal of unbound dye. |
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Sterility |
Sterile. (e-beams sterilization) |